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Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study

Citation

Kaspar, F and Jelinek, HF and Perkins, S and Al-Aubaidy, HA and deJong, B and Butkowski, E, Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study, Mediators of Inflammation Article 5474837. ISSN 0962-9351 (2016) [Refereed Article]


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Copyright Statement

Copyright 2016 Felix Kaspar et al. Licensed under Creative Commons Attribution License

DOI: doi:10.1155/2016/5474837

Abstract

Objective: This study compared acute and late effect of single-bout endurance training (ET) and high-intensity interval training (HIIT) on the plasma levels of four inflammatory cytokines and C-reactive protein and insulin-like growth factor 1.

Design: Cohort study with repeated-measures design. Methods. Seven healthy untrained volunteers completed a single bout of ET and HIIT on a cycle ergometer. ET and HIIT sessions were held in random order and at least 7 days apart. Blood was drawn before the interventions and 30 min and 2 days after the training sessions. Plasma samples were analyzed with ELISA for the interleukins (IL), IL-1β, IL-6, and IL-10, monocyte chemoattractant protein-1 (MCP-1), insulin growth factor 1 (IGF-1), and C-reactive protein (CRP). Statistical analysis was with Wilcoxon signed-rank tests.

Result: ET led to both a significant acute and long-term inflammatory response with a significant decrease at 30 minutes after exercise in the IL-6/IL-10 ratio (−20%; p=0.047) and a decrease of MCP-1 (−17.9%; p=0.03).

Conclusion: This study demonstrates that ET affects the inflammatory response more adversely at 30 minutes after exercise compared to HIIT. However, this is compensated by a significant decrease in MCP-1 at two days associated with a reduced risk of atherosclerosis.

Item Details

Item Type:Refereed Article
Keywords:inflammation, exercise, efficiency, MCP-1, cytokines, biomarkers
Research Division:Medical and Health Sciences
Research Group:Medical Biochemistry and Metabolomics
Research Field:Medical Biochemistry and Metabolomics not elsewhere classified
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Al-Aubaidy, HA (Dr Hayder Al-Aubaidy)
ID Code:108234
Year Published:2016
Web of Science® Times Cited:2
Deposited By:Medicine (Discipline)
Deposited On:2016-04-14
Last Modified:2018-03-07
Downloads:72 View Download Statistics

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