eCite Digital Repository

Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study


Kaspar, F and Jelinek, HF and Perkins, S and Al-Aubaidy, HA and deJong, B and Butkowski, E, Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study, Mediators of Inflammation Article 5474837. ISSN 0962-9351 (2016) [Refereed Article]


Copyright Statement

Copyright 2016 Felix Kaspar et al. Licensed under Creative Commons Attribution License

DOI: doi:10.1155/2016/5474837


Objective: This study compared acute and late effect of single-bout endurance training (ET) and high-intensity interval training (HIIT) on the plasma levels of four inflammatory cytokines and C-reactive protein and insulin-like growth factor 1.

Design: Cohort study with repeated-measures design. Methods. Seven healthy untrained volunteers completed a single bout of ET and HIIT on a cycle ergometer. ET and HIIT sessions were held in random order and at least 7 days apart. Blood was drawn before the interventions and 30 min and 2 days after the training sessions. Plasma samples were analyzed with ELISA for the interleukins (IL), IL-1β, IL-6, and IL-10, monocyte chemoattractant protein-1 (MCP-1), insulin growth factor 1 (IGF-1), and C-reactive protein (CRP). Statistical analysis was with Wilcoxon signed-rank tests.

Result: ET led to both a significant acute and long-term inflammatory response with a significant decrease at 30 minutes after exercise in the IL-6/IL-10 ratio (−20%; p=0.047) and a decrease of MCP-1 (−17.9%; p=0.03).

Conclusion: This study demonstrates that ET affects the inflammatory response more adversely at 30 minutes after exercise compared to HIIT. However, this is compensated by a significant decrease in MCP-1 at two days associated with a reduced risk of atherosclerosis.

Item Details

Item Type:Refereed Article
Keywords:inflammation, exercise, efficiency, MCP-1, cytokines, biomarkers
Research Division:Biomedical and Clinical Sciences
Research Group:Medical biochemistry and metabolomics
Research Field:Medical biochemistry and metabolomics not elsewhere classified
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Al-Aubaidy, HA (Dr Hayder Al-Aubaidy)
ID Code:108234
Year Published:2016
Web of Science® Times Cited:21
Deposited By:Medicine
Deposited On:2016-04-14
Last Modified:2018-03-07
Downloads:137 View Download Statistics

Repository Staff Only: item control page