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Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study

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posted on 2023-05-18, 18:42 authored by Kaspar, F, Jelinek, HF, Perkins, S, Al-Aubaidy, HA, deJong, B, Butkowski, E

Objective: This study compared acute and late effect of single-bout endurance training (ET) and high-intensity interval training (HIIT) on the plasma levels of four inflammatory cytokines and C-reactive protein and insulin-like growth factor 1.

Design: Cohort study with repeated-measures design. Methods. Seven healthy untrained volunteers completed a single bout of ET and HIIT on a cycle ergometer. ET and HIIT sessions were held in random order and at least 7 days apart. Blood was drawn before the interventions and 30 min and 2 days after the training sessions. Plasma samples were analyzed with ELISA for the interleukins (IL), IL-1β, IL-6, and IL-10, monocyte chemoattractant protein-1 (MCP-1), insulin growth factor 1 (IGF-1), and C-reactive protein (CRP). Statistical analysis was with Wilcoxon signed-rank tests.

Result: ET led to both a significant acute and long-term inflammatory response with a significant decrease at 30 minutes after exercise in the IL-6/IL-10 ratio (−20%; p = 0.047) and a decrease of MCP-1 (−17.9%; p = 0.03).

Conclusion: This study demonstrates that ET affects the inflammatory response more adversely at 30 minutes after exercise compared to HIIT. However, this is compensated by a significant decrease in MCP-1 at two days associated with a reduced risk of atherosclerosis.

History

Publication title

Mediators of Inflammation

Article number

5474837

Number

5474837

Pagination

1-6

ISSN

0962-9351

Department/School

Tasmanian School of Medicine

Publisher

Carfax Publishing

Place of publication

United Kingdom

Rights statement

Copyright © 2016 Felix Kaspar et al. Licensed under Creative Commons Attribution License

Repository Status

  • Open

Socio-economic Objectives

Clinical health not elsewhere classified

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