Kaspar, F and Jelinek, HF and Perkins, S and Al-Aubaidy, HA and deJong, B and Butkowski, E, Acute-phase inflammatory response to single-bout HIIT and endurance training: a comparative study, Mediators of Inflammation Article 5474837. ISSN 0962-9351 (2016) [Refereed Article]
Copyright © 2016 Felix Kaspar et al. Licensed under Creative Commons Attribution License
Objective: This study compared acute and late effect of single-bout endurance training (ET) and high-intensity interval training (HIIT) on the plasma levels of four inflammatory cytokines and C-reactive protein and insulin-like growth factor 1.
Design: Cohort study with repeated-measures design. Methods. Seven healthy untrained volunteers completed a single bout of ET and HIIT on a cycle ergometer. ET and HIIT sessions were held in random order and at least 7 days apart. Blood was drawn before the interventions and 30 min and 2 days after the training sessions. Plasma samples were analyzed with ELISA for the interleukins (IL), IL-1β, IL-6, and IL-10, monocyte chemoattractant protein-1 (MCP-1), insulin growth factor 1 (IGF-1), and C-reactive protein (CRP). Statistical analysis was with Wilcoxon signed-rank tests.
Result: ET led to both a significant acute and long-term inflammatory response with a significant decrease at 30 minutes after exercise in the IL-6/IL-10 ratio (−20%; p = 0.047) and a decrease of MCP-1 (−17.9%; p = 0.03).
Conclusion: This study demonstrates that ET affects the inflammatory response more adversely at 30 minutes after exercise compared to HIIT. However, this is compensated by a significant decrease in MCP-1 at two days associated with a reduced risk of atherosclerosis.
|Item Type:||Refereed Article|
|Keywords:||inflammation, exercise, efficiency, MCP-1, cytokines, biomarkers|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Medical biochemistry and metabolomics|
|Research Field:||Medical biochemistry and metabolomics not elsewhere classified|
|Objective Group:||Clinical health|
|Objective Field:||Clinical health not elsewhere classified|
|UTAS Author:||Al-Aubaidy, HA (Dr Hayder Al-Aubaidy)|
|Web of Science® Times Cited:||21|
|Downloads:||131 View Download Statistics|
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