eCite Digital Repository
Parental history of diabetes in an insulin-treated diabetes registry
Citation
Riley, MD and Blizzard, CL and McCarty, DJ and Senator, GB and Dwyer, T and Zimmet, P, Parental history of diabetes in an insulin-treated diabetes registry, Diabetic Medicine, 14, (1) pp. 35-41. ISSN 0742-3071 (1997) [Refereed Article]
DOI: doi:10.1002/(SICI)1096-9136(199701)14:1<35::AID-DIA296>3.3.CO;2-9
Abstract
To confirm observations of an excess maternal transmission of Type 2 (non-insulin dependent) diabetes mellitus in a setting which minimizes potential biases and confounders, we explored the patterns of maternal and paternal diabetes in a cohort (n=1775) of subjects with insulin-treated diabetes mellitus (ITDM) in Tasmania, Australia. In order to identify individuals with Type 1 diabetes or insulin-treated Type 2 diabetes, cases were classified into groups based on their age at diagnosis and subsequent time to commencement of insulin. Individuals initially diagnosed younger than age 30 (predominantly Type 1 diabetes cases) reported a similar percentage of mothers and fathers with diabetes, but individuals diagnosed at age 30 or older (predominantly insulin-treated Type 2 diabetes) reported a maternal excess of diabetes. Having an elevated body mass index was associated with a higher frequency of maternal diabetes, but not of paternal diabetes. Because both childhood-onset Type 1 diabetes and adult-onset insulin-treated Type 2 diabetes cases were subject to the same potential study biases, these results offer support for an excess maternal role in Type 2 diabetes transmission.
Item Details
Item Type: | Refereed Article |
---|---|
Research Division: | Health Sciences |
Research Group: | Epidemiology |
Research Field: | Epidemiology not elsewhere classified |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Clinical health not elsewhere classified |
UTAS Author: | Riley, MD (Mr Malcolm Riley) |
UTAS Author: | Blizzard, CL (Professor Leigh Blizzard) |
UTAS Author: | Dwyer, T (Professor Terry Dwyer) |
ID Code: | 10819 |
Year Published: | 1997 |
Web of Science® Times Cited: | 20 |
Deposited By: | Menzies Centre |
Deposited On: | 1997-08-01 |
Last Modified: | 2011-08-11 |
Downloads: | 0 |
Repository Staff Only: item control page