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Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls


Bobridge, KS and Haines, GL and Mori, TA and Beilin, LJ and Oddy, WH and Sherriff, J and O'Sullivan, TA, Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls, Journal of Human Hypertension, 27, (4) pp. 217-224. ISSN 0950-9240 (2013) [Refereed Article]

DOI: doi:10.1038/jhh.2012.3


Evidence that fructose intake may modify blood pressure is generally limited to adult populations. This study examined cross-sectional associations between dietary intake of fructose, serum uric acid and blood pressure in 814 adolescents aged 13-15 years participating in the Western Australian Pregnancy Cohort (Raine) Study. Energy-adjusted fructose intake was derived from 3-day food records, serum uric acid concentration was assessed using fasting blood and resting blood pressure was determined using repeated oscillometric readings. In multivariate linear regression models, we did not see a significant association between fructose and blood pressure in boys or girls. In boys, fructose intake was independently associated with serum uric acid (P<0.01), and serum uric acid was independently associated with systolic blood pressure (P<0.01) and mean arterial pressure (P<0.001). Although there are independent associations, there is no direct relationship between fructose intake and blood pressure. Our data suggest that gender may influence these relationships in adolescence, with significant associations observed more frequently in boys than girls.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Nutrition and Dietetics
Research Field:Clinical and Sports Nutrition
Objective Division:Health
Objective Group:Public Health (excl. Specific Population Health)
Objective Field:Nutrition
Author:Oddy, WH (Professor Wendy Oddy)
ID Code:107912
Year Published:2013
Web of Science® Times Cited:32
Deposited By:Menzies Institute for Medical Research
Deposited On:2016-03-31
Last Modified:2017-11-03

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