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Associations of surgical and nonsurgical weight loss with knee musculature: a cohort study of obese adults

Citation

Teichtahl, AJ and Wluka, AE and Wang, Y and Wijethilake, PN and Strauss, B and Proietto, J and Dixon, JB and Jones, G and Forbes, A and Cicuttini, FM, Associations of surgical and nonsurgical weight loss with knee musculature: a cohort study of obese adults, Surgery for Obesity and Related Diseases, 12, (1) pp. 158-164. ISSN 1550-7289 (2016) [Refereed Article]

Copyright Statement

Copyright 2016 American Society for Metabolic and Bariatric Surgery

DOI: doi:10.1016/j.soard.2015.04.021

Abstract

BACKGROUND: Marked weight loss reduces lean body mass and quadriceps thickness. It is unclear whether muscle loss varies according to the method of weight loss.

OBJECTIVE: This study compared the association of surgical versus nonsurgical weight loss with change in vastus medialis (VM) properties in obese adults.

METHODS: Twenty obese patients (body mass index≥30 kg/m2) who lost weight via laparoscopic gastric banding were matched for weight loss with obese patients who lost weight nonsurgically. The thickness and fat infiltration of VM were assessed at baseline and a mean of 2.4 years later.

RESULTS: After adjusting for confounders, the annual change in VM thickness was -2.9% in the surgical group and -.5% for the nonsurgical group (P = .02). There was also a tendency toward an increased risk for VM fat infiltration to be reduced when weight loss occurred nonsurgically (OR 5.1, 95% CI .8-32.8; P = .09).

CONCLUSIONS: Compared with nonsurgical weight loss, laparoscopic gastric banding was associated with greater VM muscle thickness loss. Relative to laparoscopic gastric banding, there was also a tendency toward an increased risk for VM fat infiltration to be reduced with nonsurgical weight loss. Close attention to preserving muscle properties at the knee when significant amounts of weight loss have occurred is required. Physical therapy may be important in the management of patients after laparoscopic gastric banding in an attempt to preserve skeletal muscle mass.

Item Details

Item Type:Refereed Article
Keywords:Obesity, Muscle, Weight, Bariatric, Knee
Research Division:Medical and Health Sciences
Research Group:Clinical Sciences
Research Field:Rheumatology and Arthritis
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Skeletal System and Disorders (incl. Arthritis)
Author:Jones, G (Professor Graeme Jones)
ID Code:107454
Year Published:2016
Web of Science® Times Cited:2
Deposited By:Menzies Institute for Medical Research
Deposited On:2016-03-16
Last Modified:2017-11-01
Downloads:0

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