eCite Digital Repository

Symptoms and their recognition in adult haemodialysis patients: interactions with quality of life


Raj, R and Ahuja, KDK and Frandsen, M and Jose, M, Symptoms and their recognition in adult haemodialysis patients: interactions with quality of life, Nephrology, 22, (3) pp. 228-233. ISSN 1320-5358 (2017) [Refereed Article]


Copyright Statement

Copyright 2016 Asian Pacific Society of Nephrology

DOI: doi:10.1111/nep.12754


Aim: We investigated the symptom burden in adults on haemodialysis; the recognition of symptoms by nurses and nephrologists; and the relationship between symptoms and quality of life.

Methods: In this cross-sectional observational study, symptoms and quality of life in hemodialysis patients were determined using validated surveys. Nurses and nephrologists independently estimated their patients‟ symptoms, and these estimates were compared with patient responses (sensitivity; kappa values for inter-rater agreement). Associations between symptoms and quality of life were assessed using multi-level regression.

Results: Forty-three patients, 18 nurses and 3 nephrologists participated. The commonest symptoms (95%CI) reported by patients were weakness, 69% (53 to 82); poor mobility, 44% (29 to 60); and drowsiness, 44% (29 to 60). Sensitivity less than 50% was seen towards 11 of 17 symptoms in nurse ratings compared with 15 of 17 in nephrologist ratings. Agreement with patient symptom ratings was mostly ‘fair’ (0.21–0.4), with nurses' scores showing greater agreement than nephrologists'. Physical, mental and kidney disease component summary scores of quality of life were negatively associated with total symptom score and the number of ‘major’ symptoms (r2 values 0.3–0.36); while with multivariate regression, 50% to 60% of the variance in these scores was accounted for by parsimonious models containing symptoms such as pain and poor mobility.

Conclusion: Symptom burden worsened quality of life scores in haemodialysis patients. Clinician recognition of symptom burden was inaccurate, although nurses were more accurate than nephrologists. Using patient-completed surveys or including dialysis nurse feedback in routine outpatient settings may help improve symptom recognition by nephrologists.

Item Details

Item Type:Refereed Article
Keywords:nurse’s role, quality of life, renal dialysis, surveys and questionnaires, symptom assessment
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Nephrology and urology
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Raj, R (Dr Rajesh Raj)
UTAS Author:Ahuja, KDK (Dr Kiran Ahuja)
UTAS Author:Frandsen, M (Dr Mai Frandsen)
UTAS Author:Jose, M (Professor Matthew Jose)
ID Code:107406
Year Published:2017 (online first 2016)
Web of Science® Times Cited:28
Deposited By:Medicine
Deposited On:2016-03-15
Last Modified:2022-08-29
Downloads:84 View Download Statistics

Repository Staff Only: item control page