Raj, R and Ahuja, KDK and Frandsen, M and Jose, M, Symptoms and their recognition in adult haemodialysis patients: interactions with quality of life, Nephrology, 22, (3) pp. 228-233. ISSN 1320-5358 (2017) [Refereed Article]
Copyright 2016 Asian Pacific Society of Nephrology
Aim: We investigated the symptom burden in adults on haemodialysis; the recognition of symptoms by nurses and nephrologists; and the relationship between symptoms and quality of life.
Methods: In this cross-sectional observational study, symptoms and quality of life in hemodialysis patients were determined using validated surveys. Nurses and nephrologists independently estimated their patients‟ symptoms, and these estimates were compared with patient responses (sensitivity; kappa values for inter-rater agreement). Associations between symptoms and quality of life were assessed using multi-level regression.
Results: 43 patients, 18 nurses and 3 nephrologists participated. The commonest symptoms (95%CI) reported by patients were: weakness, 69%(53 to 82); poor mobility, 44%(29 to 60); and drowsiness,44%(29 to 60). Sensitivity less than 50% was seen towards 11 of 17 symptoms in nurse ratings compared to 15 of 17 in nephrologist ratings. Agreement with patient symptom ratings was mostly "fair" (0.21 - 0.4), with nurses‟ scores showing greater agreement than nephrologists‟. Physical, mental and kidney disease component summary scores of quality of life were negatively associated with total symptom score and the number of major‟ symptoms (r2 values 0.3-0.36); while with multivariate regression, 50 to 60% of the variance in these scores was accounted for by parsimonious models containing symptoms such as pain and poor mobility.
|Item Type:||Refereed Article|
|Research Division:||Medical and Health Sciences|
|Research Group:||Clinical Sciences|
|Research Field:||Nephrology and Urology|
|Objective Group:||Clinical Health (Organs, Diseases and Abnormal Conditions)|
|Objective Field:||Urogenital System and Disorders|
|Author:||Raj, R (Dr Rajesh Raj)|
|Author:||Ahuja, KDK (Dr Kiran Ahuja)|
|Author:||Frandsen, M (Dr Mai Frandsen)|
|Author:||Jose, M (Professor Matthew Jose)|
|Year Published:||2017 (online first 2016)|
|Web of Science® Times Cited:||1|
|Deposited By:||Medicine (Discipline)|
|Downloads:||1 View Download Statistics|
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