University of Tasmania
Browse

File(s) under permanent embargo

The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

journal contribution
posted on 2023-05-18, 17:45 authored by Vanni CarusoVanni Caruso, Hagglund, MG, Badiali, L, Bagchi, S, Roshanbin, S, Ahmad, T, Schioth, HB, Fredriksson, R
The Rhodopsin family is a class of integral membrane proteins belonging to G protein-coupled receptors (GPCRs). To date, several orphan GPCRs are still uncharacterized and in this study we present an anatomical characterization of the GPR162 protein and an attempt to describe its functional role. Our results show that GPR162 is widely expressed in GABAergic as well as other neurons within the mouse hippocampus, whereas extensive expression is observed in areas related to energy homeostasis and hedonic feeding such as hypothalamus, amygdala and ventral tegmental area, regions known to be involved in the regulation of palatable food consumption.

History

Publication title

Gene

Volume

553

Pagination

1-6

ISSN

0378-1119

Department/School

School of Pharmacy and Pharmacology

Publisher

Elsevier Science Bv

Place of publication

Netherlands

Rights statement

© 2014 Elsevier B.V. All rights reserved.

Repository Status

  • Restricted

Socio-economic Objectives

Diagnosis of human diseases and conditions

Usage metrics

    University Of Tasmania

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC