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Devil facial tumor disease
journal contribution
posted on 2023-05-18, 17:29 authored by Ruth PyeRuth Pye, Gregory WoodsGregory Woods, Kreiss, ADevil facial tumor disease (DFTD) is an emergent transmissible cancer exclusive to Tasmanian devils (Sarcophilus harrisii) and threatening the species with extinction in the wild. Research on DFTD began 10 years ago, when nothing was known about the tumor and little about the devils. The depth of knowledge gained since then is impressive, with research having addressed significant aspects of the disease and the devils’ responses to it. These include the cause and pathogenesis of DFTD, the immune response of the devils and the immune evasion mechanisms of the tumor, the transmission patterns of DFTD, and the impacts of DFTD on the ecosystem. This review aims to collate this information and put it into the context of conservation strategies designed to mitigate the impacts of DFTD on the devil and the Tasmanian ecosystem.
History
Publication title
Veterinary PathologyVolume
53Issue
4Pagination
726-736ISSN
0300-9858Department/School
Menzies Institute for Medical ResearchPublisher
Amer Coll Vet PathologistPlace of publication
810 East 10Th Street, Lawrence, USA, Ks, 66044Rights statement
Copyright The Authors 2015Repository Status
- Restricted