eCite Digital Repository

Patient characteristics and antithrombotic prescribing patterns in patients with atrial fibrillation in Tasmania


Bista, D and Chalmers, L and Peterson, GM and Bereznicki, LRE, Patient characteristics and antithrombotic prescribing patterns in patients with atrial fibrillation in Tasmania, Clinical and Applied Thrombosis - Hemostasis, 23, (5) pp. 438-444. ISSN 1076-0296 (2017) [Refereed Article]

Copyright Statement

Copyright 2015 The Authors

DOI: doi:10.1177/1076029615623375


Limited data are available on atrial fibrillation (AF) and its clinical management and outcomes from an Australian perspective. This study was designed to examine the patient characteristics and antithrombotic treatment patterns among patients with AF in Tasmania, Australia. This retrospective observational study reviewed and followed patients with AF admitted to Tasmania’s 3 major hospitals between January 2011 and June 2012. Patients were excluded if they had only 1 episode of AF that reverted spontaneously or upon cardioversion without any documented recurrences. We reviewed the records of 2502 patients (≥ 18 years), and 1469 were subsequently included in the study. The mean (± standard deviation [SD]) age of the patients was 76 (± 12.3) years. The mean (± SD) CHADS2 score was 2.1 (± 1.3), and 65.7% had a score ≥ 2. In total, only 55.6% of patients with CHADS2 score ≥ 2 were receiving anticoagulation and 9.9% were not receiving any antithrombotic treatment, whereas 85.4% of those at low risk (score 0) were on antithrombotic therapy. Hospitalization was associated with a significant increase in the rate of combination (antiplatelet plus anticoagulant) therapy (P < .001). Suboptimal use of antithrombotic therapy highlights the need to improve AF management in our jurisdiction.

Item Details

Item Type:Refereed Article
Keywords:atrial fibrillation, antithrombotic treatment, hospitalization, patient characteristics, stroke, warfarin, elderly
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacy and pharmacy practice
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Bista, D (Ms Durga Bista)
UTAS Author:Chalmers, L (Dr Leanne Chalmers)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
UTAS Author:Bereznicki, LRE (Professor Luke Bereznicki)
ID Code:106754
Year Published:2017 (online first 2015)
Web of Science® Times Cited:4
Deposited By:Pharmacy
Deposited On:2016-02-19
Last Modified:2017-12-08

Repository Staff Only: item control page