Limited data are available on atrial fibrillation (AF) and its clinical management and outcomes from an Australian perspective. This study was designed to examine the patient characteristics and antithrombotic treatment patterns among patients with AF in Tasmania, Australia. This retrospective observational study reviewed and followed patients with AF admitted to Tasmania’s 3 major hospitals between January 2011 and June 2012. Patients were excluded if they had only 1 episode of AF that reverted spontaneously or upon cardioversion without any documented recurrences. We reviewed the records of 2502 patients (≥ 18 years), and 1469 were subsequently included in the study. The mean (± standard deviation [SD]) age of the patients was 76 (± 12.3) years. The mean (± SD) CHADS₂ score was 2.1 (± 1.3), and 65.7% had a score ≥ 2. In total, only 55.6% of patients with CHADS₂ score ≥ 2 were receiving anticoagulation and 9.9% were not receiving any antithrombotic treatment, whereas 85.4% of those at low risk (score 0) were on antithrombotic therapy. Hospitalization was associated with a significant increase in the rate of combination (antiplatelet plus anticoagulant) therapy (P < .001). Suboptimal use of antithrombotic therapy highlights the need to improve AF management in our jurisdiction.

Item Type:	Refereed Article
Keywords:	atrial fibrillation, antithrombotic treatment, hospitalization, patient characteristics, stroke, warfarin, elderly
Research Division:	Medical and Health Sciences
Research Group:	Pharmacology and Pharmaceutical Sciences
Research Field:	Clinical Pharmacy and Pharmacy Practice
Objective Division:	Health
Objective Group:	Other Health
Objective Field:	Health not elsewhere classified
Author:	Bista, D (Ms Durga Bista)
Author:	Chalmers, L (Dr Leanne Chalmers)
Author:	Peterson, GM (Professor Gregory Peterson)
Author:	Bereznicki, LRE (Professor Luke Bereznicki)
ID Code:	106754
Year Published:	2017 (online first 2015)
Deposited By:	Pharmacy
Deposited On:	2016-02-19
Last Modified:	2017-12-08
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