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Piston-cylinder based micro liquid–liquid extraction with GC–qMS for trace analysis of targeted chlorinated organic compounds in water
Citation
Luong, J and Gras, R and Gras, K and Shellie, RA, Piston-cylinder based micro liquid-liquid extraction with GC-qMS for trace analysis of targeted chlorinated organic compounds in water, Canadian Journal of Chemistry, 93, (11) pp. 1283-1289. ISSN 0008-4042 (2015) [Refereed Article]
DOI: doi:10.1139/cjc-2015-0307
Abstract
A fast and reliable approach for the measurement of sub parts-per-billion levels of targeted chlorinated compounds like tetrachloroethane, hexachloroethane, hexachlorobutadiene, pentachlorobenzene, and hexachlorobenzene in various water matrices such as waste water is described. The method employed a novel piston-cylinder-based micro liquid–liquid extraction technique using hexane as an extraction solvent. The device, known commercially as the MIXXOR, substantially accelerates extraction time by a factor of more than 100 times and reduces solvent consumption by a factor of 25 times when compared with the solvent extraction technique using wrist-action mechanical agitation. A recently introduced 6% cyanopropylphenyl –94% dimethylpolysiloxane capillary column offering a high degree of inertness was used for the separation of the analytes. A quadrupole mass spectrometer equipped with a triple-axis detector was also employed to enhance the instrument detection limit. With this technique, a complete separation for the analytes in water can be conducted in less than 10 min using a three-port SilFlow planar microfluidic device for back-flushing. Repeatability of retention times for all compounds were found to be less than 0.04% (n = 10). The compounds cited can be analyzed from 1 ng/mL to 10 μg/mL, with a detection limit and correlation coefficient of at least 0.5 ng/mL and 0.999, respectively. A relative precision of less than 1.2% relative standard deviation (RSD) (n = 20) at the 50 ng/mL level, with analyte recovery of greater than 99% (n = 3) from 10 ng/mL to 10 μg/mL, was obtained.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | micro liquid-liquid extraction, piston-cylinder based extraction, DB-624UI column, planar microfluidics, triple-axis detector |
| Research Division: | Chemical Sciences |
| Research Group: | Analytical Chemistry |
| Research Field: | Separation Science |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Chemical Sciences |
| UTAS Author: | Luong, J (Mr Jim Luong) |
| UTAS Author: | Gras, R (Ms Ronda Gras) |
| UTAS Author: | Shellie, RA (Associate Professor Robert Shellie) |
| ID Code: | 106674 |
| Year Published: | 2015 |
| Web of Science® Times Cited: | 1 |
| Deposited By: | Austn Centre for Research in Separation Science |
| Deposited On: | 2016-02-17 |
| Last Modified: | 2017-10-30 |
| Downloads: | 0 |
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