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Sleep quality among people living with chronic non-cancer pain: findings from the Pain and Opioids IN Treatment (POINT) cohort


Lintzeris, N and Moodley, R and Campbell, G and Larance, B and Bruno, R and Nielsen, S and Degenhardt, L, Sleep quality among people living with chronic non-cancer pain: findings from the Pain and Opioids IN Treatment (POINT) cohort, Clinical Journal of Pain, 32, (5) pp. 380-387. ISSN 0749-8047 (2016) [Refereed Article]

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Copyright © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of the article is prohibited.

DOI: doi:10.1097/AJP.0000000000000282


Study Objectives: To examine sleep disturbances in the POINT cohort study consisting of participants prescribed long-term opioids for chronic non-cancer pain (CNCP), and to examine the relationship between sleep and measures of pain, physical and mental health, substance use and medication use at the baseline interview.

Methods: A convenience sample of 1243 participants with current CNCP and prescription opioid use were recruited from community settings and underwent a structured interview examining subjective sleep symptoms (Medical Outcomes Study (MOS) Sleep Scale and the Sleep Problems Index (SLP-9)), pain severity and interference using the Brief Pain Inventory, mental and physical health symptoms, recent substance and medication use. Linear regression models assessed independent predictors of SLP-9 scores.

Results: Median hours of sleep per night was 6 (IQR 5-7.5) with 26% reporting optimal sleep (seven to eight hours), and a mean SLP-9 score of 47.3 (SD = 20.9). On multivariate analysis, age, frequent/severe headaches, total BPI pain severity and pain interference scores, moderate to severe anxiety or depression, daily tobacco use and past week benzodiazepine use were significant predictors of SLP-9 scores and sleep quality. Higher MOS respiratory impairment was observed in males, those with high BMI, frequent/severe headaches, high pain interference scores and in patients taking anticonvulsants and antipsychotic medications. Opioid use was not associated with SLP-9 or respiratory sleep impairment.

Conclusions: High levels of sleep problems were reported in this community sample of CNCP patients, and were associated with mental health problems and increased medication use. Non-medication approaches to addressing sleep problems should be prioritised in this population.

Item Details

Item Type:Refereed Article
Keywords:sleep, chronic pain, insomnia, opioid, cohort study, sleep
Research Division:Psychology
Research Group:Other psychology
Research Field:Other psychology not elsewhere classified
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Public health (excl. specific population health) not elsewhere classified
UTAS Author:Bruno, R (Associate Professor Raimondo Bruno)
ID Code:106559
Year Published:2016 (online first 2015)
Web of Science® Times Cited:6
Deposited By:Psychology
Deposited On:2016-02-13
Last Modified:2018-03-27

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