Lintzeris, N and Moodley, R and Campbell, G and Larance, B and Bruno, R and Nielsen, S and Degenhardt, L, Sleep quality among people living with chronic non-cancer pain: findings from the Pain and Opioids IN Treatment (POINT) cohort, Clinical Journal of Pain, 32, (5) pp. 380-387. ISSN 0749-8047 (2016) [Refereed Article]
Copyright © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of the article is prohibited.
Study Objectives: To examine sleep disturbances in the POINT cohort study consisting of participants prescribed long-term opioids for chronic non-cancer pain (CNCP), and to examine the relationship between sleep and measures of pain, physical and mental health, substance use and medication use at the baseline interview.
Methods: A convenience sample of 1243 participants with current CNCP and prescription opioid use were recruited from community settings and underwent a structured interview examining subjective sleep symptoms (Medical Outcomes Study (MOS) Sleep Scale and the Sleep Problems Index (SLP-9)), pain severity and interference using the Brief Pain Inventory, mental and physical health symptoms, recent substance and medication use. Linear regression models assessed independent predictors of SLP-9 scores.
Results: Median hours of sleep per night was 6 (IQR 5-7.5) with 26% reporting optimal sleep (seven to eight hours), and a mean SLP-9 score of 47.3 (SD = 20.9). On multivariate analysis, age, frequent/severe headaches, total BPI pain severity and pain interference scores, moderate to severe anxiety or depression, daily tobacco use and past week benzodiazepine use were significant predictors of SLP-9 scores and sleep quality. Higher MOS respiratory impairment was observed in males, those with high BMI, frequent/severe headaches, high pain interference scores and in patients taking anticonvulsants and antipsychotic medications. Opioid use was not associated with SLP-9 or respiratory sleep impairment.
Conclusions: High levels of sleep problems were reported in this community sample of CNCP patients, and were associated with mental health problems and increased medication use. Non-medication approaches to addressing sleep problems should be prioritised in this population.
|Item Type:||Refereed Article|
|Keywords:||sleep, chronic pain, insomnia, opioid, cohort study, sleep|
|Research Division:||Psychology and Cognitive Sciences|
|Research Group:||Other Psychology and Cognitive Sciences|
|Research Field:||Psychology and Cognitive Sciences not elsewhere classified|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Substance Abuse|
|Author:||Bruno, R (Associate Professor Raimondo Bruno)|
|Year Published:||2016 (online first 2015)|
|Web of Science® Times Cited:||1|
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