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Association between myocardial mechanics and iIschemic LV remodeling


D'Elia, N and D'hooge, J and Marwick, TH, Association between myocardial mechanics and iIschemic LV remodeling, JACC: Cardiovascular Imaging, 8, (12) pp. 1430-1443. ISSN 1936-878X (2015) [Refereed Article]

Copyright Statement

Copyright 2015 American College of Cardiology Foundation

DOI: doi:10.1016/j.jcmg.2015.10.005


The outcomes associated with heart failure after myocardial infarction are still poor. Both global and regional left ventricular (LV) remodeling are associated with the progression of the post-infarct patient to heart failure, but although global remodeling can be accurately measured, regional LV remodeling has been more difficult to investigate. Preliminary evidence suggests that post-MI assessment of LV mechanics using stress and strain may predict global (and possibly regional) LV remodeling. A method of predicting both global and regional LV remodeling might facilitate earlier, targeted, and more extensive clinical intervention in those most likely to benefit from novel interventions such as cell therapy.

Item Details

Item Type:Refereed Article
Keywords:ischemic heart disease, left ventricular mechanics, left ventricular remodeling, left ventricular strain, left ventricular wall stress, left ventricular curvature
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:D'Elia, N (Mr Nic D'Elia)
UTAS Author:Marwick, TH (Professor Tom Marwick)
ID Code:106219
Year Published:2015
Web of Science® Times Cited:33
Deposited By:Menzies Institute for Medical Research
Deposited On:2016-02-02
Last Modified:2017-11-02

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