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Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
Citation
MacLeod, MR and McLean, AL and Kyriakopoulou, A and Serghiou, S and de Wilde, A and Sherratt, N and Hirst, T and Hemblade, R and Bahor, Z and Nunes-Fonseca, C and Potluru, A and Thomson, A and Baginskitae, J and Egan, K and Vesterinen, H and Currie, GL and Churilov, L and Howells, DW and Sena, ES, Risk of Bias in Reports of In Vivo Research: A Focus for Improvement, Public Library of Science Biology, 13, (11) Article e1002273. ISSN 1544-9173 (2015) [Refereed Article]
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Copyright Statement
Copyright 2015 Macleod et al. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
DOI: doi:10.1371/journal.pbio.1002273
Abstract
The reliability of experimental findings depends on the rigour of experimental design. Here we show limited reporting of measures to reduce the risk of bias in a random sample of life sciences publications, significantly lower reporting of randomisation in work published in journals of high impact, and very limited reporting of measures to reduce the risk of bias in publications from leading United Kingdom institutions. Ascertainment of differences between institutions might serve both as a measure of research quality and as a tool for institutional efforts to improve research quality.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Research Division: | Medical and Health Sciences |
| Research Group: | Other Medical and Health Sciences |
| Research Field: | Medical and Health Sciences not elsewhere classified |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Medical and Health Sciences |
| Author: | Howells, DW (Professor David Howells) |
| ID Code: | 106202 |
| Year Published: | 2015 |
| Web of Science® Times Cited: | 43 |
| Deposited By: | Medicine (Discipline) |
| Deposited On: | 2016-02-02 |
| Last Modified: | 2016-09-13 |
| Downloads: | 38 View Download Statistics |
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