eCite Digital Repository
Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial
Citation
Titov, N and Dear, BF and Staples, LG and Terides, MD and Karin, E and Sheehan, J and Johnston, L and Gandy, M and Fogliati, VJ and Wootton, BM and McEvoy, PM, Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial, Journal of Anxiety Disorders, 35 pp. 88-102. ISSN 0887-6185 (2015) [Refereed Article]
![]() | PDF 1Mb |
Copyright Statement
Copyright 2015 The Authors Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/
DOI: doi:10.1016/j.janxdis.2015.08.002
Abstract
Disorder-specific cognitive behavior therapy (DS-CBT) is effective at treating major depressive disorder (MDD) while transdiagnostic CBT (TD-CBT) addresses both principal and comorbid disorders by targeting underlying and common symptoms. The relative benefits of these two models of therapy have not been determined. Participants with MDD (n = 290) were randomly allocated to receive an internet delivered TD-CBT or DS-CBT intervention delivered in either clinician-guided (CG-CBT) or self-guided (SG-CBT) formats. Large reductions in symptoms of MDD (Cohen’s d ≥ 1.44; avg. reduction ≥ 45%) and moderate-to-large reductions in symptoms of comorbid generalised anxiety disorder (Cohen’s d ≥ 1.08; avg. reduction ≥ 43%), social anxiety disorder (Cohen’s d ≥ 0.65; avg. reduction ≥ 29%) and panic disorder (Cohen’s d ≥ 0.45; avg. reduction ≥ 31%) were found. No marked or consistent differences were observed across the four conditions, highlighting the efficacy of different forms of CBT at treating MDD and comorbid disorders.
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | major depressive disorder, anxiety disorders, treatment, transdiagnostic, disorder-specific, self- guided, therapist-guided, internet, 24-month follow-up, randomized controlled trial |
Research Division: | Health Sciences |
Research Group: | Health services and systems |
Research Field: | Mental health services |
Objective Division: | Health |
Objective Group: | Public health (excl. specific population health) |
Objective Field: | Mental health |
UTAS Author: | Wootton, BM (Dr Bethany Wootton) |
ID Code: | 106035 |
Year Published: | 2015 |
Web of Science® Times Cited: | 90 |
Deposited By: | Psychology |
Deposited On: | 2016-01-25 |
Last Modified: | 2016-08-15 |
Downloads: | 146 View Download Statistics |
Repository Staff Only: item control page