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Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial
Citation
Titov, N and Dear, BF and Staples, LG and Terides, MD and Karin, E and Sheehan, J and Johnston, L and Gandy, M and Fogliati, VJ and Wootton, BM and McEvoy, PM, Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial, Journal of Anxiety Disorders, 35 pp. 88-102. ISSN 0887-6185 (2015) [Refereed Article]
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Copyright Statement
Copyright 2015 The Authors Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/
DOI: doi:10.1016/j.janxdis.2015.08.002
Abstract
Disorder-specific cognitive behavior therapy (DS-CBT) is effective at treating major depressive disorder (MDD) while transdiagnostic CBT (TD-CBT) addresses both principal and comorbid disorders by targeting underlying and common symptoms. The relative benefits of these two models of therapy have not been determined. Participants with MDD (n = 290) were randomly allocated to receive an internet delivered TD-CBT or DS-CBT intervention delivered in either clinician-guided (CG-CBT) or self-guided (SG-CBT) formats. Large reductions in symptoms of MDD (Cohen’s d ≥ 1.44; avg. reduction ≥ 45%) and moderate-to-large reductions in symptoms of comorbid generalised anxiety disorder (Cohen’s d ≥ 1.08; avg. reduction ≥ 43%), social anxiety disorder (Cohen’s d ≥ 0.65; avg. reduction ≥ 29%) and panic disorder (Cohen’s d ≥ 0.45; avg. reduction ≥ 31%) were found. No marked or consistent differences were observed across the four conditions, highlighting the efficacy of different forms of CBT at treating MDD and comorbid disorders.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | major depressive disorder, anxiety disorders, treatment, transdiagnostic, disorder-specific, self- guided, therapist-guided, internet, 24-month follow-up, randomized controlled trial |
| Research Division: | Health Sciences |
| Research Group: | Health services and systems |
| Research Field: | Mental health services |
| Objective Division: | Health |
| Objective Group: | Public health (excl. specific population health) |
| Objective Field: | Mental health |
| UTAS Author: | Wootton, BM (Dr Bethany Wootton) |
| ID Code: | 106035 |
| Year Published: | 2015 |
| Web of Science® Times Cited: | 90 |
| Deposited By: | Psychology |
| Deposited On: | 2016-01-25 |
| Last Modified: | 2016-08-15 |
| Downloads: | 146 View Download Statistics |
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