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Why 'RedUSe'? Rationale for studying the clinical outcomes of sedative reduction in the residential aged care setting


Hoyle, D and Westbury, JL and Bindoff, IK and Peterson, GM, Why 'RedUSe'? Rationale for studying the clinical outcomes of sedative reduction in the residential aged care setting, 13th National Conference of Emerging Researchers in Ageing, 24-25 September 2014, Adelaide, Australia, pp. 42. (2015) [Conference Extract]

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Research consistently shows high usage of psycholeptic medication (predominantly antipsychotics and benzodiazepines) in many residential aged care facilities (RACFs). Antipsychotics are often employed to treat behavioural and psychological symptoms of dementia (BPSD) while benzodiazepines are frequently used to alleviate anxiety and sleep disturbances, despite the risk of severe adverse effects and limited effectiveness. Generally, antipsychotic reduction has not been shown to significantly affect BPSD; however, both deterioration and improvement in BPSD has been detected in sub-groups of residents depending on severity of baseline behaviour and initial antipsychotic dose. Furthermore, research is conflicting as to whether or not psycholeptic reduction diminishes rates of falls, and subsequent fractures. Currently, the "Reducing the Use of Sedatives" (RedUSe) project (Westbury, Jackson, Gee, & Peterson, 2010) is being expanded nationally to promote appropriate use of psycholeptics in RACFs. Clinical outcome measures, such as BPSD and falls, which have often been absent from similar implementation projects, will be monitored to observe the effect of psycholeptic reduction on residents.

Item Details

Item Type:Conference Extract
Keywords:Sedatives; Agitation; Falls; Quality of life; Residential Aged Care; Reduction
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacology and therapeutics
Objective Division:Health
Objective Group:Specific population health (excl. Indigenous health)
Objective Field:Health related to ageing
UTAS Author:Hoyle, D (Dr Daniel Hoyle)
UTAS Author:Westbury, JL (Associate Professor Juanita Breen)
UTAS Author:Bindoff, IK (Dr Ivan Bindoff)
UTAS Author:Peterson, GM (Professor Gregory Peterson)
ID Code:105382
Year Published:2015
Deposited By:Pharmacy
Deposited On:2015-12-22
Last Modified:2015-12-22

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