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National Cancer Institute Prostate Cancer Genetics Workshop

Citation

Catalona, WJ and Bailey-Wilson, JE and Camp, NJ and Chanock, SJ and Cooney, KA and Easton, DF and Eeles, RA and Fitzgerald, LM and Freedman, ML and Gudmundsson, J and Kittles, RA and Marguiles, EH and McGuire, BB and Ostrander, EA and Rebbeck, TR and Stanford, JL and Thibodeau, SN and White, JS and Isaacs, WB, National Cancer Institute Prostate Cancer Genetics Workshop, Cancer Research, 71, (10) pp. 3442-3446. ISSN 0008-5472 (2011) [Letter or Note in Journal]

Copyright Statement

Copyright 2011 American Association for Cancer Research

DOI: doi:10.1158/0008-5472.CAN-11-0314

Abstract

Compelling evidence supports a genetic component to prostate cancer (PC) susceptibility and aggressiveness. Recent genome-wide association studies (GWAS) have identified >30 single nucleotide polymorphisms associated with PC susceptibility. It remains unclear, however, whether such genetic variants are associated with disease aggressiveness—one of the most important questions in PC research today. To help clarify this and substantially expand research in the genetic determinants of PC aggressiveness, the first National Cancer Institute Prostate Cancer Genetics Workshop assembled researchers to develop plans for a large new research consortium and patient cohort. The workshop reviewed the prior work in this area and addressed the practical issues in planning future studies. With new DNA sequencing technology, the potential application of sequencing information to patient care is emerging. The workshop, therefore, included state-of-the-art presentations by experts on new genotyping technologies, including sequencing and associated bioinformatics issues, which are just beginning to be applied to cancer genetics.

Item Details

Item Type:Letter or Note in Journal
Keywords:Prostate Cancer
Research Division:Medical and Health Sciences
Research Group:Oncology and Carcinogenesis
Research Field:Cancer Genetics
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cancer and Related Disorders
Author:Fitzgerald, LM (Dr Liesel Fitzgerald)
ID Code:104093
Year Published:2011
Web of Science® Times Cited:6
Deposited By:Menzies Institute for Medical Research
Deposited On:2015-11-03
Last Modified:2018-03-22
Downloads:0

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