The processes of gene duplication, loss, and lineage sorting can result in incongruence between the phylogenies of genes and those of species. This incongruence complicates the task of inferring the latter from the former. We describe the use of reconciled trees to reconstruct the history of a gene tree with respect to a species tree. Reconciled trees allow the history of the gene tree to be visualized and also quantify the relationship between the two trees. The cost of a reconciled tree is the total number of duplications and gene losses required to reconcile a gene tree with its species tree. We describe the use of heuristic searches to find the species tree which yields the reconciled tree with the lowest cost. This method can be used to infer species trees from one or more gene trees.

Item Type:	Refereed Article
Keywords:	phylogenetics, gene trees, reconciliation
Research Division:	Biological Sciences
Research Group:	Genetics
Research Field:	Genetics not elsewhere classified
Objective Division:	Expanding Knowledge
Objective Group:	Expanding knowledge
Objective Field:	Expanding knowledge in the biological sciences
UTAS Author:	Charleston, MA (Professor Michael Charleston)
ID Code:	103686
Year Published:	1997
Web of Science® Times Cited:	293
Deposited By:	Mathematics and Physics
Deposited On:	2015-10-26
Last Modified:	2015-11-16
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