eCite Digital Repository

Does youth adiposity, or change in adiposity from youth to adulthood, predict metabolically healthy obesity in adulthood?

Citation

Smith, KJ and Bessell, E and Magnussen, CG and Dwyer, T and Venn, AJ, Does youth adiposity, or change in adiposity from youth to adulthood, predict metabolically healthy obesity in adulthood?, Pediatric Obesity, 11 pp. 349-353. ISSN 2047-6302 (2015) [Refereed Article]

Copyright Statement

Copyright 2015 World Obesity

DOI: doi:10.1111/ijpo.12065

Abstract

Background: Individuals with metabolically healthy obesity (MHO) do not have the metabolic complications usually associated with obesity.

Objective: To examine whether youth adiposity, or change in adiposity from youth to adulthood, predicts MHO 20 years later.

Methods: A national sample of 2410 Australian participants had height, weight and waist circumference (WC) measured in 1985 (715 years old) and 20042006 (2636 years old). A fasting blood sample was taken in 20042006. MHO was defined as body mass index (BMI) ≥30 kg m−2, normal fasting glucose (<5.6 mmol L−1), triglycerides (<1.695 mmol L−1), high-density lipoprotein-cholesterol (>1.036 mmol L−1 men, >1.295 mmol L−1 women), blood pressure (<130/85 mmHg) and no medication for these conditions. Relative risks (RR) were calculated using log binomial regression and expressed per unit of youth BMI (or WC) z-score or change in BMI (or WC) z-score from youth to adulthood, adjusted for sex and youth age.

Results: In total 323 individuals were obese at follow-up, 79 (24.5%) were MHO. Adult MHO was not associated with youth BMI (RR: 1.00, 95%CI: 0.85-1.19) or WC (RR: 0.93, 95%CI: 0.79-1.11). Individuals were less likely to be MHO if they had larger increases in BMI (BMI RR: 0.74, 95%CI: 0.57-0.97) or WC (RR: 0.70, 95%CI: 0.55-0.90) from youth to adulthood.

Conclusions: Change in adiposity from youth to adulthood predicted adult MHO better than youth adiposity alone.

Item Details

Item Type:Refereed Article
Keywords:body mass index, metabolic health, metabolically healthy obesity, waist circumference
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cardiovascular System and Diseases
Author:Smith, KJ (Dr Kylie Smith)
Author:Bessell, E (Miss Erica Bessell)
Author:Magnussen, CG (Dr Costan Magnussen)
Author:Dwyer, T (Professor Terry Dwyer)
Author:Venn, AJ (Professor Alison Venn)
ID Code:103031
Year Published:2015
Web of Science® Times Cited:2
Deposited By:Menzies Institute for Medical Research
Deposited On:2015-09-16
Last Modified:2017-11-04
Downloads:0

Repository Staff Only: item control page