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SABIO-RKódatabase for biochemical reaction kinetics

Citation

Wittig, U and Kania, R and Golebiewski, M and Rey, M and Shi, L and Jong, L and Algaa, E and Weidemann, A and Sauer-Danzwith, H and Mir, S and Krebs, O and Bittkowski, M and Wetsch, E and Rojas, I and Muller, W, Scientific Databases and Visualization Group, Heidelberg Institute for Theoretical Studies (HITS gGmbH), SABIO-RK database for biochemical reaction kinetics, Nucleic Acids Research, 40 pp. D790-D796. ISSN 0305-1048 (2012) [Refereed Article]


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Copyright Statement

Copyright 2011 The Authors This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

DOI: doi:10.1093/nar/gkr1046

Abstract

SABIO-RK (http://sabio.h-its.org/) is a web accessible database storing comprehensive information about biochemical reactions and their kinetic properties. SABIO-RK offers standardized data manually extracted from the literature and data directly submitted from lab experiments. The database content includes kinetic parameters in relation to biochemical reactions and their biological sources with no restriction on any particular set of organisms. Additionally, kinetic rate laws and corresponding equations as well as experimental conditions are represented. All the data are manually curated and annotated by biological experts, supported by automated consistency checks. SABIO-RK can be accessed via web-based user interfaces or automatically via web services that allow direct data access by other tools. Both interfaces support the export of the data together with its annotations in SBML (Systems Biology Markup Language), e.g. for import in modelling tools.

Item Details

Item Type:Refereed Article
Keywords:biochemical processes, enzymes, metabolism, kinetics, databases
Research Division:Biological Sciences
Research Group:Biochemistry and Cell Biology
Research Field:Enzymes
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Biological Sciences
Author:Jong, L (Dr Lenneke Jong)
ID Code:102644
Year Published:2012
Web of Science® Times Cited:80
Deposited By:IMAS Research and Education Centre
Deposited On:2015-09-01
Last Modified:2017-11-07
Downloads:244 View Download Statistics

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