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Investigation on selectivity of mercaptopropylsilica and silver nanoparticles-functionalised mercaptopropylsilica


Sandron, S and Paull, B and Nesterenko, PN, Investigation on selectivity of mercaptopropylsilica and silver nanoparticles-functionalised mercaptopropylsilica, Current Chromatography, 2, (2) pp. 122-135. ISSN 2213-2406 (2015) [Refereed Article]

Copyright Statement

Copyright 2015 Bentham Science Publishers

DOI: doi:10.2174/2213240602666150706180219


Mercaptopropylsilica and silver nanoparticle (AgNP)-coated mercaptopropylsilica (Nucleosil 300, particle size 5 m and pore size 10 nm) were prepared and their suitability as stationary phases for reversed-phase high-performance liquid chromatography (RP-HPLC) was evaluated. The retention mechanism was investigated for both ionogenic and non-ionogenic compounds using 150 x 4.6 mm i.d. columns, with emphasis on non-specific hydrophobic interactions and the possibility of specific hydrogen-bonding and donor-acceptor interactions between solutes and stationary phases. The retention of more than 40 substances including pyridines, anilines, phenols, benzoic acids and others was investigated. A different selectivity was obtained in the case of a series of anilines and pyridines. However, both phases showed a non-orthogonal retention mechanism, the latter being related to electron donor-acceptor interactions. The presence of hydrophilic interaction liquid chromatography (HILIC) retention behavior was demonstrated for mercaptopropylsilica phase.

Item Details

Item Type:Refereed Article
Keywords:coordination, hydrogen bonding, hydrophilic interaction liquid chromatography, mercaptopropylsilica, reversedphase high performance liquid chromatography, silver nanoparticles, stationary phase
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Sandron, S (Dr Sara Sandron)
UTAS Author:Paull, B (Professor Brett Paull)
UTAS Author:Nesterenko, PN (Professor Pavel Nesterenko)
ID Code:102221
Year Published:2015
Funding Support:Australian Research Council (DP130101518)
Deposited By:Chemistry
Deposited On:2015-08-05
Last Modified:2016-05-17

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