Smith, K and Mattick, RP and Bruno, R and Nielsen, S and Cohen, M and Campbell, G and Larance, B and Farrell, M and Degenhardt, L, Factors associated with the development of depression in chronic non-cancer pain patients following the onset of opioid treatment for pain, Journal of Affective Disorders, 184 pp. 72-80. ISSN 0165-0327 (2015) [Refereed Article]
© 2015 Elsevier B.V. All rights reserved.
Method: Participants (N = 1418) were a national sample prescribed opioids for chronic non-cancer pain. Age at onset of depression, pain and commencement of opioid medications were collected via structured interview.
Results: Six in 10 (61%) reported lifetime depression; of those, almost half developed depression after pain and after they started opioid medications (48%). Variables associated with post-opioid depression included lower pain self-efficacy and poorer social support, younger onset of opioid use, and difficulties and concerns with opioid medications.
Conclusions: The findings highlight the importance of monitoring for the emergence of mood dysfunction, particularly for those starting opioids for pain at a younger age, and consideration of psychological treatments that address self-efficacy that appears to be associated with post-opioid depression.
|Item Type:||Refereed Article|
|Keywords:||depression, chronic pain, pharmaceutical opioids, self-efficacy|
|Research Division:||Psychology and Cognitive Sciences|
|Research Field:||Psychology not elsewhere classified|
|Objective Group:||Public Health (excl. Specific Population Health)|
|Objective Field:||Substance Abuse|
|Author:||Bruno, R (Associate Professor Raimondo Bruno)|
|Funding Support:||National Health and Medical Research Council (APP1022522)|
|Web of Science® Times Cited:||9|
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