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Pharmaceutical opioid use and dependence among people living with chronic pain: associations observed within the Pain and Opioids in Treatment (POINT) Cohort
Citation
Campbell, G and Nielsen, S and Larance, B and Bruno, R and Mattick, R and Hall, W and Lintzeris, N and Cohen, M and Smith, K and Degenhardt, L, Pharmaceutical opioid use and dependence among people living with chronic pain: associations observed within the Pain and Opioids in Treatment (POINT) Cohort, Pain Medicine, 16, (9) pp. 1745-1758. ISSN 1526-4637 (2015) [Refereed Article]
Copyright Statement
Copyright 2016 American Academy of Pain Medicine
Abstract
Design: Baseline data were obtained from a national sample of 1,424 people across Australia (median 58 years, 55% female and experiencing pain for a median of 10 years), who had been prescribed opioids for CNCP. Current opioid consumption was estimated in oral morphine equivalent (OME; mg per day), and ICD-10 pharmaceutical opioid dependence was assessed using the Composite International Diagnostic Interview.
Results: Current opioid consumption varied widely: 8.8% were taking <20 mg OME per day, 52.1% were taking 21-90 mg OME, 24.3% were taking 91-199 mg OME, and 14.8% were taking >= 200 mg OME. Greater daily OME consumption was associated with higher odds of multiple physical and mental health issues, aberrant opioid use, problems associated with opioid medication and opioid dependence. A significant minority, 8.5%, met criteria for lifetime ICD-10 pharmaceutical opioid dependence and 4.7% met criteria for past year ICD-10 pharmaceutical opioid dependence. Multivariate analysis found past-year dependence was independently associated with being younger, exhibiting more aberrant behaviors and having a history of benzodiazepine dependence.
Conclusions: In this population of people taking opioids for CNCP, consumption of higher doses was associated with increased risk of problematic behaviors, and was more likely among people with a complex profile of physical and mental health problems.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | opioids, chronic pain, dependence |
| Research Division: | Psychology and Cognitive Sciences |
| Research Group: | Psychology |
| Research Field: | Psychology not elsewhere classified |
| Objective Division: | Health |
| Objective Group: | Public Health (excl. Specific Population Health) |
| Objective Field: | Substance Abuse |
| UTAS Author: | Bruno, R (Associate Professor Raimondo Bruno) |
| ID Code: | 101837 |
| Year Published: | 2015 |
| Funding Support: | National Health and Medical Research Council (APP1022522) |
| Web of Science® Times Cited: | 36 |
| Deposited By: | Psychology |
| Deposited On: | 2015-07-12 |
| Last Modified: | 2017-11-07 |
| Downloads: | 0 |
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