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Exploring the molecular mechanism of karrikins and strigolactones


Scaffidi, A and Waters, MT and Bond, CS and Dixon, KW and Smith, SM and Ghisalberti, EL and Flematti, GR, Exploring the molecular mechanism of karrikins and strigolactones, Bioorganic and Medicinal Chemistry Letters, 22, (11) pp. 3743-3746. ISSN 0960-894X (2012) [Refereed Article]

Copyright Statement

Copyright 2012 Published by Elsevier Ltd.

DOI: doi:10.1016/j.bmcl.2012.04.016


Karrikins and strigolactones are novel plant growth regulators that contain similar molecular features, but very little is known about how they elicit responses in plants. A tentative molecular mechanism has previously been proposed involving a Michael-type addition for both compounds. Through structure–activity studies with karrikins, we now propose an alternative mechanism for karrikin and strigolactone mode of action that involves hydrolysis of the butenolide ring.

Item Details

Item Type:Refereed Article
Keywords:karrikins, strigolactones, signalling
Research Division:Biological Sciences
Research Group:Plant biology
Research Field:Plant physiology
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the biological sciences
UTAS Author:Smith, SM (Professor Steven Smith)
ID Code:101631
Year Published:2012
Web of Science® Times Cited:65
Deposited By:Plant Science
Deposited On:2015-06-26
Last Modified:2017-11-02

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