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A central role for the peroxisomal membrane in glyoxylate cycle function
Citation
Kunze, M and Pracharoenwattana, I and Smith, SM and Hartig, A, A central role for the peroxisomal membrane in glyoxylate cycle function, Biochimica et Biophysica Acta: Molecular Cell Research, 1763, (12) pp. 1441-1452. ISSN 0167-4889 (2006) [Refereed Article]
Copyright Statement
Copyright 2006 Elsevier B.V.
DOI: doi:10.1016/j.bbamcr.2006.09.009
Abstract
The glyoxylate cycle provides the means to convert C2-units to C4-precursors for biosynthesis, allowing growth on fatty acids and C2-compounds. The conventional view that the glyoxylate cycle is contained within peroxisomes in fungi and plants is no longer valid. Glyoxylate cycle enzymes are located both inside and outside the peroxisome. Thus, the operation of the glyoxylate cycle requires transport of several intermediates across the peroxisomal membrane. Glyoxylate cycle progression is also dependent upon mitochondrial metabolism. An understanding of the operation and regulation of the glyoxylate cycle, and its integration with cellular metabolism, will require further investigation of the participating metabolite transporters in the peroxisomal membrane.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | glyoxylate cycle, peroxisomes, membrane transport, metabolic compartmentation, saccharomyces cerevisiae, Arabidopsis thaliana |
| Research Division: | Biological Sciences |
| Research Group: | Plant Biology |
| Research Field: | Plant Physiology |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding Knowledge |
| Objective Field: | Expanding Knowledge in the Biological Sciences |
| Author: | Smith, SM (Professor Steven Smith) |
| ID Code: | 101511 |
| Year Published: | 2006 |
| Web of Science® Times Cited: | 89 |
| Deposited By: | Plant Science |
| Deposited On: | 2015-06-25 |
| Last Modified: | 2015-09-24 |
| Downloads: | 0 |
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